Cover Image

Synthesis and anti-microbial screening of novel schiff bases of 3-amino-2-methyl quinazolin 4-(3H)-one

In the present study, novel Schiff bases were synthesized by condensation of 3-amino-2-methyl quinazolin-4-(3H)-ones with different aromatic aldehydes. The 3-amino-2-methyl quinazolin-4-(3H)-one was synthesized from anthranilic acid via the 2-methyl benzoxazin-4-one. The chemical structures of the s...

Full description

Saved in:

Bibliographic Details
Main Authors:	Govindaraj Saravanan (Author), Perumal Pannerselvam (Author), Chinnasamy Rajaram Prakash (Author)
Format:	Book
Published:	Wolters Kluwer Medknow Publications, 2010-01-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Synthesis, characterization, and analgesic activity of novel schiff base of isatin derivatives
by: Rajaram Prakash Chinnasamy, et al.
Published: (2010)

Synthesis, characterization, cytotoxic screening, and density functional theory studies of new derivatives of quinazolin-4(3H)-one Schiff bases
by: Rezvan Rezaee Nasab, et al.
Published: (2017)

Synthesis of New 3-Substituted Quinazolin-4(3H)-one Compounds Via Linking of Some Five-Membered Ring Heterocyclic Moieties With Quinazolin-4(3H)-one Nucleus
by: Mohammed Al-iraqi, et al.
Published: (2021)

Synthesis and antitumor activity of certain 2,3,6-trisubstituted quinazolin-4(3H)-one derivatives
by: Safinaz E. Abbas, et al.
Published: (2013)

Design, Synthesis and molecular docking study of hybrids of quinazolin-4(3H)-one as anticancer agents
by: Sukanya Nara, et al.

Synthesis and evaluation of anticancer, antiphospholipases, antiproteases, and antimetabolic syndrome activities of some 3H-quinazolin-4-one derivatives
by: Nahed N. E. El-Sayed, et al.
Published: (2019)

Antioxidant and Cytotoxic Activity of New Polyphenolic Derivatives of Quinazolin-4(3H)-one: Synthesis and In Vitro Activities Evaluation
by: Raluca Pele, et al.
Published: (2022)

Design, synthesis, molecular docking and anticonvulsant evaluation of novel 6-iodo-2-phenyl-3-substituted-quinazolin-4(3H)-ones
by: Mohamed-Kamal Ibrahim, et al.
Published: (2015)

Design, Synthesis, Pharmacological Evaluation of Quinazolin-4(3H)-Ones Bearing Urea Functionality as Potential VEGFR-2 Inhibitors
by: Al-Sanea MM, et al.
Published: (2024)

Synthesis and cytotoxic evaluation of some new 3-(2-(2-phenylthiazol-4-yl) ethyl)-quinazolin-4(3H) one derivatives with potential anticancer effects
by: Leila Hosseinzadeh, et al.
Published: (2017)

Synthesis and physicochemical properties 4-((R))amino)-5-methyl-4H-1,2,4-triazole-3-thiols
by: T. V. Kravchenko, et al.
Published: (2018)

Antibacterial Effects of Quinazolin-4(3<i>H</i>)-One Functionalized-Conjugated Silver Nanoparticles
by: Abdulkader Masri, et al.
Published: (2019)

Quinazolin-4(3H)-one based potential multiple tyrosine kinase inhibitors with excellent cytotoxicity
by: Tebyan O. Mirgany, et al.
Published: (2021)

New Quinazolin-4(3H)-One Derivatives Incorporating Isoxazole Moiety as Antioxidant Agents: Synthesis, Structural Characterization, and Theoretical DFT Mechanistic Study
by: Yassine Rhazi, et al.
Published: (2024)

ANTIMICROBIAL ACTIVITY STUDY OF NEW QUINAZOLIN-4(3H)-ONES AGAINST STAPHYLOCOCCUS AUREUS AND STREPTOCOCCUS PNEUMONIAE
by: M. A. Samotrueva, et al.
Published: (2021)

Synthesis, in-vitro antimicrobial and antitubercular screening of Schiff bases of 3-amino-1-phenyl-4- [2-(4-phenyl-1,3-thiazol-2-yl) hydrazin-1-ylidene]-4,5-dihydro-1H-pyrazol-5-one
by: K K Sivakumar, et al.
Published: (2013)

Radioiodination and biodistribution of newly synthesized 3-benzyl-2-([3-methoxybenzyl]thio)benzo[g]quinazolin-4-(3H)-one in tumor bearing mice
by: Rashad Al-Salahi, et al.
Published: (2018)

Synthesis and structure of some new Schiff bases, derivatives of 2-((4-((R-benzylidene)amino)-5-(2-fluorophenyl)-4H-1,2,4-triazole-3-yl)thio)acetohydrazides
by: Ye. S. Pruglo
Published: (2018)

Analgesic activity of 4-amino-5-methyl-4H-1,2,4-triazol-3-thiones
by: T. V. Kravchenko, et al.
Published: (2018)

SYNTHESIS AND ANTIMICROBIAL EVALUATION OF 2-[(SUBSTITUEDPHENYL)-5-(1-PHENYL-3-(PIPERAZINYL)PYRIDO[3,2-f]QUINAZOLIN-4(1H)-YL]-1,3,4-THIADIAZOLES
by: Ranjana Dubey, et al.
Published: (2016)

Synthesis and Characterization of Methyl Amino Polystyrene as Resin Material of Chromatography
by: Herman Herman, et al.
Published: (2018)

Actoprotective activity of 6-monosubstituted 3-R-6,7-dihydro-2H-[1,2,4]triazino-[2,3-c]quinazoline-2-ones
by: O. S. Kolomoets, et al.
Published: (2016)

Design, synthesis, and biological evaluation of quinazolin-4(3H)-one derivatives co-targeting poly(ADP-ribose) polymerase-1 and bromodomain containing protein 4 for breast cancer therapy
by: Xiaosa Chang, et al.
Published: (2021)

COMPUTATION DESIGN OF QUINAZOLINE-4(3H)-ON DERIVATIVES AS CYCLOOXYGENASE-2 (COX-2) INHIBITOR
by: Anita Puspa Widiyana
Published: (2021)

Quinazolin-4-one/3-cyanopyridin-2-one Hybrids as Dual Inhibitors of EGFR and BRAF<sup>V600E</sup>: Design, Synthesis, and Antiproliferative Activity
by: Lamya H. Al-Wahaibi, et al.
Published: (2023)

Discussion of antimicrobial and antifungal activity of 4-amino-5-methyl-4H-1,2,4-triazole-3-thiol
by: T. V. Kravchenko, et al.
Published: (2017)

Synthesis Of Some Substituted 1,2,5-Oxadiazino [2-3,b] Quinazoline And Some 1,3-Oxazole Derivatives
by: Yassir S. Mohamad
Published: (2013)

New Quinazolin-4(3<i>H</i>)-one Derivatives Incorporating Hydrazone and Pyrazole Scaffolds as Antimicrobial Agents Targeting DNA Gyraze Enzyme
by: Eman M. Mohi El-Deen, et al.
Published: (2022)

Synthesis and Biological Evaluation of Some New 3-Aryl-2-thioxo-2,3-dihydroquinazolin-4(1<i>H</i>)-ones and 3-Aryl-2-(benzylthio)quinazolin-4(3<i>H</i>)-ones as Antioxidants; COX-2, LDHA, α-Glucosidase and α-Amylase Inhibitors; and Anti-Colon Carcinoma and Apoptosis-Inducing Agents
by: Nahed Nasser Eid El-Sayed, et al.
Published: (2023)

Synthesis and anticancer activity of new quinazoline derivatives
by: Hatem A. Abuelizz, et al.
Published: (2017)

Synthesis, structure and properties of 7-((4-amino-5-thio-1,2,4-triazole-3-yl)methyl)-theophylline derivatives
by: A. S. Hotsulia, et al.
Published: (2020)

DFT-analysis of protolytic equivalents of 5-(aryl)-4-(methyl,amino)-1,2,4-triazole-3(2H)-thione
by: O. A. Bihdan, et al.
Published: (2022)

Synthesis and anticonvulsant activity of 6-methyl-2-((2-oxo-2-arylethyl)thio)pyrimidin-4(3 H)-one derivatives and products of their cyclization
by: Hanna I. Severina, et al.
Published: (2019)

Novel Thiazole-Fused [4,5-<i>g</i>] or [5,4-<i>g</i>]Quinazolin-8-ones and Their Quinazoline Analogues: Synthesis and Biological Evaluation
by: Nathan Broudic, et al.
Published: (2024)

Anti-Tubercular Properties of 4-Amino-5-(4-Fluoro-3- Phenoxyphenyl)-4<i>H</i>-1,2,4-Triazole-3-Thiol and Its Schiff Bases: Computational Input and Molecular Dynamics
by: Katharigatta N. Venugopala, et al.
Published: (2020)

Synthesis of some new N3 substituted 5-hydroxy-7-methyl-3H-thiazolo[4,5-b]pyridin-2-ones as potential biologically active compounds
by: T. I. Chaban, et al.
Published: (2019)

Design, synthesis and structure-activity studies of amino acids conjugated quinazolinone-Schiff's bases as potential antioxidant and anti-inflammatory agents
by: Santosh Kumar Verma, et al.
Published: (2022)

Design and biological evaluation of 3-substituted quinazoline-2,4(1H,3H)-dione derivatives as dual c-Met/VEGFR-2-TK inhibitors
by: Abdelfattah Hassan, et al.
Published: (2023)

Synthesis of chalcone incorporated quinazoline derivatives as anticancer agents
by: Sapavat Madhavi, et al.
Published: (2017)

Discovery of 4-cyclopropyl-3-(2-((1-cyclopropyl-1H-pyrazol-4-yl) amino) quinazolin-6-yl)-N-(3-(trifluoromethyl) phenyl) benzamides as potent discoidin domain receptor inhibitors for the treatment of idiopathic pulmonary fibrosis
by: Qi Wang, et al.
Published: (2022)