Hyaluronic Acid-Binding, Anionic, Nanoparticles Inhibit ECM Degradation and Restore Compressive Stiffness in Aggrecan-Depleted Articular Cartilage Explants

Joint trauma results in the production of inflammatory cytokines that stimulate the secretion of catabolic enzymes, which degrade articular cartilage. Molecular fragments of the degraded articular cartilage further stimulate inflammatory cytokine production, with this process eventually resulting in...

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Main Authors: Marcus Deloney (Author), Parssa Garoosi (Author), Vanessa F. C. Dartora (Author), Blaine A. Christiansen (Author), Alyssa Panitch (Author)
Format: Book
Published: MDPI AG, 2021-09-01T00:00:00Z.
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