Generalized ROC methods for immunogenicity data analysis of vaccine phase I studies in a seropositive population
Immunogenicity data from phase 1 vaccine studies can be difficult to interpret, especially in seropositive populations and when multiple assays are used. We developed 3 statistical methods (Youden index [YI] threshold, receiver-operating characteristic relative to baseline [ROC-B], and ROC of postdo...
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Main Authors: | Li Yu (Author), Mark T. Esser (Author), Judith Falloon (Author), Tonya Villafana (Author), Harry Yang (Author) |
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Format: | Book |
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Taylor & Francis Group,
2018-11-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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