Artocarpin Targets Focal Adhesion Kinase-Dependent Epithelial to Mesenchymal Transition and Suppresses Migratory-Associated Integrins in Lung Cancer Cells

• Main Authors: Nongyao Nonpanya (Author), Kittipong Sanookpan (Author), Nicharat Sriratanasak (Author), Chanida Vinayanuwattikun (Author), Duangdao Wichadakul (Author), Boonchoo Sritularak (Author), Pithi Chanvorachote (Author)
• Format: Book
• Published: MDPI AG, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Focal adhesion kinase (FAK) controls several cancer aggressive potentials of cell movement and dissemination. As epithelial-mesenchymal transition (EMT) and the migratory-associated integrins, known influencers of metastasis, have been found to be linked with FAK activity, this study unraveled the p...