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Method development and validation of Guanfacine in rat plasma by liquid chromatographyâtandem mass spectrometry: Application to a pharmacokinetic study

A selective, sensitive and high-throughput liquid chromatographyâtandem mass spectrometry (LCâESI-MS/MS) method has been developed and validated for the quantitation of Guanfacine in rat plasma. Sample clean-up involved liquidâliquid extraction (LLE) and 100Â Î¼L of rat plasma was used. YMC BASIC co...

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Bibliographic Details
Main Authors:	Suryanarayana Murthy Goparaju (Author), Yadagiri Srinivasa Murthy Nandula (Author), Chandrasekher Bannoth Kothapalli (Author), B.R. Challa (Author), Bahlul Z. Awen (Author)
Format:	Book
Published:	Elsevier, 2013-12-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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