Dissolution Enhancement in Cocoa Extract, Combining Hydrophilic Polymers through Hot-Melt Extrusion

• প্রধান লেখক: Ludmila A. G. Pinho (লেখক), Saulo G. Souza (লেখক), Ricardo N. Marreto (লেখক), Livia L. Sa-Barreto (লেখক), Tais Gratieri (লেখক), Guilherme M. Gelfuso (লেখক), Marcilio Cunha-Filho (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2018-08-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

The aim of this study was to improve the physicochemical properties of cocoa extract (CE) using hot-melt extrusion (HME) for pharmaceutical proposes. A mixture design was applied using three distinct hydrophilic polymeric matrices (Soluplus, Plasdone S630, and Eudragit E). Systems obtained by HME we...