Dissolution Enhancement in Cocoa Extract, Combining Hydrophilic Polymers through Hot-Melt Extrusion

• Hauptverfasser: Ludmila A. G. Pinho (Verfasst von), Saulo G. Souza (Verfasst von), Ricardo N. Marreto (Verfasst von), Livia L. Sa-Barreto (Verfasst von), Tais Gratieri (Verfasst von), Guilherme M. Gelfuso (Verfasst von), Marcilio Cunha-Filho (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2018-08-01T00:00:00Z.
• Schlagworte: article
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The aim of this study was to improve the physicochemical properties of cocoa extract (CE) using hot-melt extrusion (HME) for pharmaceutical proposes. A mixture design was applied using three distinct hydrophilic polymeric matrices (Soluplus, Plasdone S630, and Eudragit E). Systems obtained by HME we...