Dissolution Enhancement in Cocoa Extract, Combining Hydrophilic Polymers through Hot-Melt Extrusion

• Κύριοι συγγραφείς: Ludmila A. G. Pinho (Συγγραφέας), Saulo G. Souza (Συγγραφέας), Ricardo N. Marreto (Συγγραφέας), Livia L. Sa-Barreto (Συγγραφέας), Tais Gratieri (Συγγραφέας), Guilherme M. Gelfuso (Συγγραφέας), Marcilio Cunha-Filho (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: MDPI AG, 2018-08-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

The aim of this study was to improve the physicochemical properties of cocoa extract (CE) using hot-melt extrusion (HME) for pharmaceutical proposes. A mixture design was applied using three distinct hydrophilic polymeric matrices (Soluplus, Plasdone S630, and Eudragit E). Systems obtained by HME we...