Dissolution Enhancement in Cocoa Extract, Combining Hydrophilic Polymers through Hot-Melt Extrusion

• Päätekijät: Ludmila A. G. Pinho (Tekijä), Saulo G. Souza (Tekijä), Ricardo N. Marreto (Tekijä), Livia L. Sa-Barreto (Tekijä), Tais Gratieri (Tekijä), Guilherme M. Gelfuso (Tekijä), Marcilio Cunha-Filho (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2018-08-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

The aim of this study was to improve the physicochemical properties of cocoa extract (CE) using hot-melt extrusion (HME) for pharmaceutical proposes. A mixture design was applied using three distinct hydrophilic polymeric matrices (Soluplus, Plasdone S630, and Eudragit E). Systems obtained by HME we...