Dissolution Enhancement in Cocoa Extract, Combining Hydrophilic Polymers through Hot-Melt Extrusion

• मुख्य लेखकों: Ludmila A. G. Pinho (लेखक), Saulo G. Souza (लेखक), Ricardo N. Marreto (लेखक), Livia L. Sa-Barreto (लेखक), Tais Gratieri (लेखक), Guilherme M. Gelfuso (लेखक), Marcilio Cunha-Filho (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2018-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The aim of this study was to improve the physicochemical properties of cocoa extract (CE) using hot-melt extrusion (HME) for pharmaceutical proposes. A mixture design was applied using three distinct hydrophilic polymeric matrices (Soluplus, Plasdone S630, and Eudragit E). Systems obtained by HME we...