The non-reconstructive treatment of complete ACL tear with biological enhancement in clinical and preclinical studies: A systematic review
Introduction: There is still controversy regarding the bio-enhanced non-reconstructive ACL treatment. Materials and methods: A search for articles in databases was performed in February 2017. The objective and subjective evaluations of clinical studies and biomechanical and histological data of prec...
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| Main Authors: | , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2018-10-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | Introduction: There is still controversy regarding the bio-enhanced non-reconstructive ACL treatment. Materials and methods: A search for articles in databases was performed in February 2017. The objective and subjective evaluations of clinical studies and biomechanical and histological data of preclinical studies were extracted. Results: Eighteen articles were included for analysis. In clinical studies, although subjective scores were significantly improved, the rate of re-operation rate was high. In preclinical studies, bio-enhancing techniques demonstrated promotion of the healing of ACL. Conclusions: The efficacy of biological enhancement cannot be validated in clinical studies. Preclinical studies showed improved biomechanical and healing potential. |
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| Item Description: | 2214-6873 10.1016/j.asmart.2018.04.002 |