Nuclear Cross-Section of Proton-Induced Reactions on Enriched ⁴⁸Ti Targets for the Production of Theranostic ⁴⁷Sc Radionuclide, ^46cSc, ^44mSc, ^44gSc, ⁴³Sc, and ⁴⁸V

• Main Authors: Liliana Mou (Author), Lucia De Dominicis (Author), Sara Cisternino (Author), Hanna Skliarova (Author), Matteo Campostrini (Author), Valentino Rigato (Author), Laura De Nardo (Author), Laura Meléndez-Alafort (Author), Juan Esposito (Author), Férid Haddad (Author), Gaia Pupillo (Author)
• Format: Book
• Published: MDPI AG, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

The cross-sections of the ⁴⁸Ti(p,x)⁴⁷Sc, ^46cSc, ^44mSc, ^44gSc, ⁴³Sc, and ⁴⁸V nuclear reactions were measured from 18 to 70 MeV, with particular attention to ⁴⁷Sc production. Enriched ⁴⁸Ti powder was deposited on an aluminum backing and the obtained targets were characterized via elastic backscattering spectroscopy at the INFN-LNL. Targets were exposed to low-intensity proton irradiation using the stacked-foils technique at the ARRONAX facility. Activated samples were measured using γ-spectrometry; the results were compared with the data int he literature and the theoretical TALYS-based values. A regular trend in the new values obtained from the different irradiation runs was noted, as well as a good agreement with the literature data, for all the radionuclides of interest: ⁴⁷Sc, ^46cSc, ^44mSc, ^44gSc, ⁴³Sc, and ⁴⁸V. ⁴⁷Sc production was also discussed, considering yield and radionuclidic purity, for different ⁴⁷Sc production scenarios.

Item Description

10.3390/ph17010026
1424-8247