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Cdkal1, a type 2 diabetes susceptibility gene, regulates mitochondrial function in adipose tissue

Objectives: Understanding how loci identified by genome wide association studies (GWAS) contribute to pathogenesis requires new mechanistic insights. Variants within CDKAL1 are strongly linked to an increased risk of developing type 2 diabetes and obesity. Investigations in mouse models have focused...

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Main Authors: Colin J. Palmer (Author), Raphael J. Bruckner (Author), Joao A. Paulo (Author), Lawrence Kazak (Author), Jonathan Z. Long (Author), Amir I. Mina (Author), Zhaoming Deng (Author), Katherine B. LeClair (Author), Jessica A. Hall (Author), Shangyu Hong (Author), Peter-James H. Zushin (Author), Kyle L. Smith (Author), Steven P. Gygi (Author), Susan Hagen (Author), David E. Cohen (Author), Alexander S. Banks (Author)
Format: Book
Published: Elsevier, 2017-10-01T00:00:00Z.
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