Cardiovascular risk in obese patients with chronic periodontitis: a clinical controlled study

• Main Authors: Juliana Rico Pires (Author), Thaís Uenoyama Dezem (Author), Eliane Marçon Barroso (Author), Benedicto Egbert Corrêa de Toledo (Author), Sally Cristina Moutinho Monteiro (Author), Alex Tadeu Martins (Author), Elizângela Partata Zuza (Author)
• Format: Book
• Published: Universidade Estadual Paulista.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 1807-2577
• Keywords: periodontal diseases; chronic periodontitis; obesity; cardiovascular diseases; Medicine; R; Dentistry; RK1-715
• Source: Revista de Odontologia da UNESP, Vol 42, Iss 3, Pp 188-195

INTRODUCTION: Studies have shown that obesity is considered a risk factor for the development of periodontal disease and cardiovascular events. OBJECTIVE: The objective was to evaluate the risk for cardiovascular diseases (CVDs) in obese patients with and without periodontal. MATERIAL AND METHOD: One hundred patients were divided into four groups: Group O - obese without chronic periodontitis (n=25); Group OP - obese with chronic periodontitis (n=25); Group NO - non-obese without chronic periodontitis (n=25); and Group NOP - non-obese with chronic periodontitis (n=25). Demographic and laboratorial data (total cholesterol, high-density lipoprotein - HDL and low-density lipoprotein - LDL, triglycerides, and glucose); anthropometric measurements (body mass index - BMI; waist circumference - WC; body fat - BF); blood pressure; and periodontal parameters (bleeding on probing - BOP, periodontal probing depth - PPD, and the clinical attachment level - CAL) were evaluated. Cardiovascular risk was obtained according to the PROCAM's score. The correlation between obesity, periodontal disease and risk for CVD was verified by Spearman's test (α = 0.05). RESULT: The group OP showed a statistically higher rate of PPD > 7 mm (11.2 ± 2.03) when compared with other groups, as well as higher levels of triglycerides, total cholesterol, and LDL (p<0.05). The risk for CVD was statistically higher in the group OP (28.1 ± 3.3) when compared with group O (16.5 ± 3.5), group NOP (12.8 ± 3.9), and group NO (7.7 ± 0.9). Obesity and periodontal disease are directly related to a moderate increase in CVD risk (r = 0.53, p <0.0001 and r = 0.62, p <0.0001, respectively). CONCLUSION: It was concluded that obesity and periodontal disease increases the risk to cardiovascular events.