Two diverse carriers are better than one: A case study in α‐particle therapy for prostate specific membrane antigen‐expressing prostate cancers

• Main Authors: Dominick Salerno (Author), Alaina Howe (Author), Omkar Bhatavdekar (Author), Anders Josefsson (Author), Jesus Pacheco‐Torres (Author), Zaver M. Bhujwalla (Author), Kathleen L. Gabrielson (Author), Stavroula Sofou (Author)
• Format: Book
• Published: Wiley, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Partial and/or heterogeneous irradiation of established (i.e., large, vascularized) tumors by α‐particles that exhibit only a 4-5 cell‐diameter range in tissue, limits the therapeutic effect, since regions not being hit by the high energy α‐particles are likely not to be killed. This study...