The Cellular and Molecular Effects of Fetoscopic Endoluminal Tracheal Occlusion in Congenital Diaphragmatic Hernia

Congenital diaphragmatic hernia (CDH) is a complex disease associated with pulmonary hypoplasia and pulmonary hypertension. Great strides have been made in our ability to care for CDH patients, specifically in the prenatal improvement of lung volume and morphology with fetoscopic endoluminal trachea...

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Main Authors: Oluyinka O. Olutoye II (Author), Walker D. Short (Author), Jamie Gilley (Author), J. D. Hammond II (Author), Michael A. Belfort (Author), Timothy C. Lee (Author), Alice King (Author), Jimmy Espinoza (Author), Luc Joyeux (Author), Krithika Lingappan (Author), Jason P. Gleghorn (Author), Sundeep G. Keswani (Author)
Format: Book
Published: Frontiers Media S.A., 2022-07-01T00:00:00Z.
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100 1 0 |a Oluyinka O. Olutoye II  |e author 
700 1 0 |a Oluyinka O. Olutoye II  |e author 
700 1 0 |a Walker D. Short  |e author 
700 1 0 |a Walker D. Short  |e author 
700 1 0 |a Jamie Gilley  |e author 
700 1 0 |a J. D. Hammond II  |e author 
700 1 0 |a Michael A. Belfort  |e author 
700 1 0 |a Michael A. Belfort  |e author 
700 1 0 |a Timothy C. Lee  |e author 
700 1 0 |a Timothy C. Lee  |e author 
700 1 0 |a Timothy C. Lee  |e author 
700 1 0 |a Alice King  |e author 
700 1 0 |a Alice King  |e author 
700 1 0 |a Alice King  |e author 
700 1 0 |a Jimmy Espinoza  |e author 
700 1 0 |a Jimmy Espinoza  |e author 
700 1 0 |a Luc Joyeux  |e author 
700 1 0 |a Luc Joyeux  |e author 
700 1 0 |a Luc Joyeux  |e author 
700 1 0 |a Krithika Lingappan  |e author 
700 1 0 |a Jason P. Gleghorn  |e author 
700 1 0 |a Sundeep G. Keswani  |e author 
700 1 0 |a Sundeep G. Keswani  |e author 
700 1 0 |a Sundeep G. Keswani  |e author 
245 0 0 |a The Cellular and Molecular Effects of Fetoscopic Endoluminal Tracheal Occlusion in Congenital Diaphragmatic Hernia 
260 |b Frontiers Media S.A.,   |c 2022-07-01T00:00:00Z. 
500 |a 2296-2360 
500 |a 10.3389/fped.2022.925106 
520 |a Congenital diaphragmatic hernia (CDH) is a complex disease associated with pulmonary hypoplasia and pulmonary hypertension. Great strides have been made in our ability to care for CDH patients, specifically in the prenatal improvement of lung volume and morphology with fetoscopic endoluminal tracheal occlusion (FETO). While the anatomic effects of FETO have been described in-depth, the changes it induces at the cellular and molecular level remain a budding area of CDH research. This review will delve into the cellular and molecular effects of FETO in the developing lung, emphasize areas in which further research may improve our understanding of CDH, and highlight opportunities to optimize the FETO procedure for improved postnatal outcomes. 
546 |a EN 
690 |a congenital diaphragmatic hernia (CDH) 
690 |a tracheal occlusion (TO) 
690 |a FETO 
690 |a pulmonary hypoplasia 
690 |a pulmonary hypertension 
690 |a pulmonary development 
690 |a Pediatrics 
690 |a RJ1-570 
655 7 |a article  |2 local 
786 0 |n Frontiers in Pediatrics, Vol 10 (2022) 
787 0 |n https://www.frontiersin.org/articles/10.3389/fped.2022.925106/full 
787 0 |n https://doaj.org/toc/2296-2360 
856 4 1 |u https://doaj.org/article/f3e4f355d8364582a2647dc7387b32b0  |z Connect to this object online.