Chondroprotective effects of a proanthocyanidin rich Amazonian genonutrient reflects direct inhibition of matrix metalloproteinases and upregulation of IGF-1 production by human chondrocytes
<p>Abstract</p> <p>Background</p> <p>The Amazonian medicinal plant Sangre de grado (<it>Croton palanostigma</it>) has traditional applications for the treatment of wound healing and inflammation. We sought to characterize two extracts (progrado and zangrado)...
Saved in:
Main Authors: | Gupta Kalpana (Author), Shukla Meenakshi (Author), Bobrowski Paul (Author), Miller Mark JS (Author), Haqqi Tariq M (Author) |
---|---|
Format: | Book |
Published: |
BMC,
2007-08-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The chrondoprotective actions of a natural product are associated with the activation of IGF-1 production by human chondrocytes despite the presence of IL-1β
by: Bobrowski Paul, et al.
Published: (2006) -
The Chondroprotective Agent ITZ-1 Inhibits Interleukin-1β-Induced Matrix Metalloproteinase-13 Production and Suppresses Nitric Oxide- Induced Chondrocyte Death
by: Haruhide Kimura, et al.
Published: (2009) -
Bioavailable constituents/metabolites of pomegranate (<it>Punica granatum </it>L) preferentially inhibit COX2 activity <it>ex vivo </it>and IL-1beta-induced PGE<sub>2 </sub>production in human chondrocytes <it>i</it><it>n vitro</it>
by: Khan Khursheed A, et al.
Published: (2008) -
Effect of a Herbal-Leucine mix on the IL-1β-induced cartilage degradation and inflammatory gene expression in human chondrocytes
by: Haqqi Tariq M, et al.
Published: (2011) -
Concomitant upregulation of matrix metalloproteinase-2 in lesions and circulating plasma of oral lichen planus
by: Lo-Lin Tsai, et al.
Published: (2009)