Treatment of menopausal symptoms by an extract from the roots of rhapontic rhubarb: the role of estrogen receptors

<p>Abstract</p> <p>A dry extract from the roots of rhapontic rhubarb (extract <it>Rheum rhaponticum </it>(L.); ERr) has been commercially available in Germany for over two decades to treat menopausal symptoms. However, the molecular basis of its clinical effectiveness r...

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Main Authors: Zierau Oliver (Author), Papke Anja (Author), Vollmer Günter (Author)
Format: Book
Published: BMC, 2010-02-01T00:00:00Z.
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Summary:<p>Abstract</p> <p>A dry extract from the roots of rhapontic rhubarb (extract <it>Rheum rhaponticum </it>(L.); ERr) has been commercially available in Germany for over two decades to treat menopausal symptoms. However, the molecular basis of its clinical effectiveness remains obscure. This article reviews the <it>in vitro </it>and <it>in vivo </it>data of its estrogenic actions, particularly those mediated by estrogen receptor-β (ERβ).</p>
Item Description:10.1186/1749-8546-5-7
1749-8546