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A bivalent cyclic RGD-siRNA conjugate enhances the antitumor effect of apatinib via co-inhibiting VEGFR2 in non-small cell lung cancer xenografts

The vascular endothelial growth factor receptor 2 (VEGFR2) is considered to be a pivotal target for anti-tumor therapy against angiogenesis of non-small cell lung cancer (NSCLC). However, effective and low-toxicity targeted therapies to inhibit VEGFR2 are still lacking. Here, biRGD-siVEGFR2 conjugat...

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Bibliographic Details
Main Authors: Lumin Liao (Author), Bohong Cen (Author), Guoxian Li (Author), Yuanyi Wei (Author), Zhen Wang (Author), Wen Huang (Author), Shuai He (Author), Yawei Yuan (Author), Aimin Ji (Author)
Format: Book
Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
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