TGF-β1-Mediated Leukocyte Cell-Derived Chemotaxin 2 Is Associated With Liver Fibrosis in Biliary Atresia

• Main Authors: Jinfeng Zhao (Author), Xiaodan Xu (Author), Qingyun Gou (Author), Qipeng Zheng (Author), Liang Ge (Author), Lingzhi Chen (Author), Cong Zhang (Author), Hui Ma (Author), Shuxiang Lin (Author), Xiaoli Hu (Author), Jianghua Zhan (Author)
• Format: Bog
• Udgivet: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Fag: article
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ObjectiveBiliary atresia (BA) presents as a severe infantile cholangiopathy disease, characterized by progressive liver fibrosis and the resulting poor prognosis. Leukocyte cell-derived chemotaxin 2 (LECT2) was proposed as the key gene associated with hepatic fibrosis in BA, but the molecular mechan...