Assessment of Binding Affinity to 5-Hydroxytryptamine 2A (5-HT2A) Receptor and Inverse Agonist Activity of Naftidrofuryl: Comparison With Those of Sarpogrelate
Abstract.: Naftidrofuryl is a peripheral vasodilator that has been clinically used in the treatment of intermittent claudication and dementia. It has 5-hydroxytryptamine 2 (5-HT2) antiserotonergic activity and selectively binds with the 5-HT2 receptor. The purpose of the present study is to assess t...
Saved in:
Main Authors: | Saida Abdel Regal Aly (Author), Murad Hossain (Author), Mohiuddin Ahmed Bhuiyan (Author), Takashi Nakamura (Author), Takafumi Nagatomo (Author) |
---|---|
Format: | Book |
Published: |
Elsevier,
2009-01-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Inverse Agonist Activity of Sarpogrelate, a Selective 5-HT2A-Receptor Antagonist, at the Constitutively Active Human 5-HT2A Receptor
by: Habib Abul Muntasir, et al.
Published: (2006) -
Identification of a Key Amino Acid of the Human 5-HT2B Serotonin Receptor Important for Sarpogrelate Binding
by: Habib Abul Muntasir, et al.
Published: (2007) -
Identification of Amino Acid Residues Important for Sarpogrelate Binding to the Human 5-Hydroxytryptamine2A Serotonin Receptor
by: Habib Abul Muntasir, et al.
Published: (2006) -
Engineered Mutation of Some Important Amino Acids in Angiotensin II Type 1 (AT1) Receptor Increases the Binding Affinity of AT1-Receptor Antagonists
by: Mohiuddin Ahmed Bhuiyan, et al.
Published: (2010) -
Oral morphine induces spinal 5‐hydroxytryptamine (5‐HT) release using an opioid receptor‐independent mechanism
by: Shingo Nakamura, et al.
Published: (2023)