Screening of Novel Antimicrobial Diastereomers of Azithromycin-Thiosemicarbazone Conjugates: A Combined LC-SPE/Cryo NMR, MS/MS and Molecular Modeling Approach

• Hoofdauteurs: Iva Habinovec (Auteur), Ivana Mikulandra (Auteur), Paula Pranjić (Auteur), Saša Kazazić (Auteur), Hana Čipčić Paljetak (Auteur), Antun Barišić (Auteur), Branimir Bertoša (Auteur), Mirjana Bukvić (Auteur), Predrag Novak (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2022-12-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

A well-known class of antibacterials, 14- and 15-membered macrolides are widely prescribed to treat upper and lower respiratory tract infections. Azithromycin is a 15-membered macrolide antibiotic possessing a broad spectrum of antibacterial potency and favorable pharmacokinetics. Bacterial resistan...