Diabetes mellitus and severity by COVID-19 in hospitalized Brazilians

• Main Authors: Thiago Santos Garces (Author), George Jó Bezerra Sousa (Author), Virna Ribeiro Feitosa Cestari (Author), Samuel Miranda Mattos (Author), Raquel Sampaio Florêncio (Author), Maria Lúcia Duarte Pereira (Author), Thereza Maria Magalhães Moreira (Author)
• Format: Book
• Published: Universidade Federal do Ceará, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

Objective: to estimate the prevalence of severity of hospitalized cases of COVID-19 and its association with diabetes mellitus. Methods: a cross-sectional study, which used secondary data from the Influenza Epidemiological Surveillance Information System, totaling 405,294 confirmed cases. To verify the association of diabetes and severity in hospitalized patients with COVID-19, Poisson regression models with robust variance estimator were used. Initially, the association of disease with outcome was verified; next, several adjustments for potential confounders were performed. Results: the prevalence of diabetes in the 405,294 hospitalized and positive cases was 25.7% (Confidence Interval: 25.5% - 25.8%). After adjustments, diabetes was found to increase the severity of COVID-19 by 19% (Confidence Interval: 1.17 - 2.21). Conclusion: a significant association of diabetes mellitus with severe cases of COVID-19 infection has been identified. Contributions to practice: the evidence generated by the study guides the risk stratification of patients and directs clinical management.

Item Description

10.15253/2175-6783.20222381354
2175-6783