Signos de Leser-trélat en un carcinoma de células en anillo de sello
80 year-old man presenting with weight loss, right hypochondrium pain and vomiting, with 1 year of symptoms evolution, was admitted. Physical exam showed multiple hyperkeratotic lesions, distribuing on trunk and dorsal region, a paraneoplasic sign knowing as Leser-Trélat sign. Multiple nodular hepa...
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| Main Authors: | , |
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| Format: | Book |
| Published: |
Sociedade Galega de Medicina Interna,
2022-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | 80 year-old man presenting with weight loss, right hypochondrium pain and vomiting, with 1 year of symptoms evolution, was admitted. Physical exam showed multiple hyperkeratotic lesions, distribuing on trunk and dorsal region, a paraneoplasic sign knowing as Leser-Trélat sign. Multiple nodular hepatic hypoechogenic formations were detected on the echography. Analytically: CEA 2627 ng/mL. CT body scan: lymphatic, pulmonary, suprarenal and hepatic metastasis, without evidence of the primary tumor. Upper Endoscopy and Colonoscopy were performed, without alterations. The Hepatic biopsy revealed: infiltration by well differentiated carcinoma, with mucus lakes and numerous signet-ring cells, whose immunohistochemical profile was compatible with origin in the gastrointestinal tract. |
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| Item Description: | 0304-4866 1989-3922 10.22546/64/2462 |