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Evaluation of Rapid Diagnostic Tests for Assessment of Hepatitis B in Resource-Limited Settings

Chronic Hepatitis B (HBV) is the most important cause of liver disease worldwide. There is a need for low-cost tests to aid in diagnosis and management of HBV infection in resource-limited settings. We evaluated the utility of several rapid diagnostic tests (RDT) in three different continents (Europ...

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Bibliographic Details
Main Authors: James S. Leathers (Author), M. Belen Pisano (Author), Viviana Re (Author), Gertine van Oord (Author), Amir Sultan (Author), Andre Boonstra (Author), Jose D. Debes (Author)
Format: Book
Published: Ubiquity Press, 2019-07-01T00:00:00Z.
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Summary:Chronic Hepatitis B (HBV) is the most important cause of liver disease worldwide. There is a need for low-cost tests to aid in diagnosis and management of HBV infection in resource-limited settings. We evaluated the utility of several rapid diagnostic tests (RDT) in three different continents (Europe, South America, Africa). The HBsAg RDT showed optimal sensitivity and specificity. The anti-HBeAb RDT showed acceptable sensitivity and excellent specificity. Our results suggest that these RDTs could be used for screening and management of HBV.
Item Description:2214-9996
10.5334/aogh.2562

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