Recent Advances in Transition-Metal-Free Late-Stage C-H and N-H Arylation of Heteroarenes Using Diaryliodonium Salts
Transition-metal-free direct arylation of C-H or N-H bonds is one of the key emerging methodologies that is currently attracting tremendous attention. Diaryliodonium salts serve as a stepping stone on the way to alternative environmentally friendly and straightforward pathways for the construction o...
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MDPI AG,
2021-07-01T00:00:00Z.
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| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | doaj_f4d27dca493e47c38a1ec2338b8d04bb | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Thierry Besson |e author |
| 700 | 1 | 0 | |a Corinne Fruit |e author |
| 245 | 0 | 0 | |a Recent Advances in Transition-Metal-Free Late-Stage C-H and N-H Arylation of Heteroarenes Using Diaryliodonium Salts |
| 260 | |b MDPI AG, |c 2021-07-01T00:00:00Z. | ||
| 500 | |a 10.3390/ph14070661 | ||
| 500 | |a 1424-8247 | ||
| 520 | |a Transition-metal-free direct arylation of C-H or N-H bonds is one of the key emerging methodologies that is currently attracting tremendous attention. Diaryliodonium salts serve as a stepping stone on the way to alternative environmentally friendly and straightforward pathways for the construction of C-C and C-heteroatom bonds. In this review, we emphasize the recent synthetic advances of late-stage C(sp2)-N and C(sp2)-C(sp2) bond-forming reactions under metal-free conditions using diaryliodonium salts as arylating reagent and its applications to the synthesis of new arylated bioactive heterocyclic compounds. | ||
| 546 | |a EN | ||
| 690 | |a diaryliodonium salts | ||
| 690 | |a C-H arylation | ||
| 690 | |a <i>N</i>-arylation | ||
| 690 | |a heteroarenes | ||
| 690 | |a metal-free | ||
| 690 | |a late-stage functionalization | ||
| 690 | |a Medicine | ||
| 690 | |a R | ||
| 690 | |a Pharmacy and materia medica | ||
| 690 | |a RS1-441 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Pharmaceuticals, Vol 14, Iss 7, p 661 (2021) | |
| 787 | 0 | |n https://www.mdpi.com/1424-8247/14/7/661 | |
| 787 | 0 | |n https://doaj.org/toc/1424-8247 | |
| 856 | 4 | 1 | |u https://doaj.org/article/f4d27dca493e47c38a1ec2338b8d04bb |z Connect to this object online. |