Exploring the HIFs, buts and maybes of hypoxia signalling in disease: lessons from zebrafish models

A low level of tissue oxygen (hypoxia) is a physiological feature of a wide range of diseases, from cancer to infection. Cellular hypoxia is sensed by oxygen-sensitive hydroxylase enzymes, which regulate the protein stability of hypoxia-inducible factor α (HIF-α) transcription factors. When stabilis...

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Bibliographic Details
Main Authors: Philip M. Elks (Author), Stephen A. Renshaw (Author), Annemarie H. Meijer (Author), Sarah R. Walmsley (Author), Fredericus J. van Eeden (Author)
Format: Book
Published: The Company of Biologists, 2015-11-01T00:00:00Z.
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