Modulation of Cytokine-Induced Astrocytic Endothelin-1 Production as a Possible New Approach to the Treatment of Multiple Sclerosis
Background: In the human central nervous system (CN), resting astrocytes do not visually show endothelin-1 (ET-1)-like immunoreactivity. In patients with multiple sclerosis (MS), an inflammatory disorder of the CNS, high levels of ET-1 are found in reactive astrocytes in demyelinated plaques. ET-1 m...
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Main Authors: | Stéphanie Hostenbach (Author), Miguel D'Haeseleer (Author), Ron Kooijman (Author), Jacques De Keyser (Author) |
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Format: | Book |
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Frontiers Media S.A.,
2020-01-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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