Defining HIV and SIV Reservoirs in Lymphoid Tissues

• Main Authors: Claire Deleage (Author), Stephen W. Wietgrefe (Author), Gregory Del Prete (Author), David R. Morcock (Author), Xing-Pei Hao (Author), Michael Piatak, Jr (Author), Julian Bess (Author), Jodi L. Anderson (Author), Katherine Perkey (Author), Cavan Reilly (Author), Joseph M. McCune (Author), Ashley T. Haase (Author), Jeffrey D. Lifson (Author), Timothy W. Schacker (Author), Jacob D. Estes (Author)
• Format: Book
• Published: Case Western Reserve University, 2016-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A primary obstacle to an HIV-1 cure is long-lived viral reservoirs, which must be eliminated or greatly reduced. Cure strategies have largely focused on monitoring changes in T cell reservoirs in peripheral blood (PB), even though the lymphoid tissues (LT) are primary sites for viral persistence. To...