Relationship between acetaldehyde concentration in mouth air and tongue coating volume

Objective Acetaldehyde is the first metabolite of ethanol and is produced in the epithelium by mucosal ALDH, while higher levels are derived from microbial oxidation of ethanol by oral microflora such as Candida species. However, it is uncertain whether acetaldehyde concentration in human breath is...

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Main Authors: Aya YOKOI (Author), Takayuki MARUYAMA (Author), Reiko YAMANAKA (Author), Daisuke EKUNI (Author), Takaaki TOMOFUJI (Author), Haruhiko KASHIWAZAKI (Author), Yutaka YAMAZAKI (Author), Manabu MORITA (Author)
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Published: University of São Paulo, 2015-02-01T00:00:00Z.
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001 doaj_f53f9965b92747a295da62e98b99a58d
042 |a dc 
100 1 0 |a Aya YOKOI  |e author 
700 1 0 |a Takayuki MARUYAMA  |e author 
700 1 0 |a Reiko YAMANAKA  |e author 
700 1 0 |a Daisuke EKUNI  |e author 
700 1 0 |a Takaaki TOMOFUJI  |e author 
700 1 0 |a Haruhiko KASHIWAZAKI  |e author 
700 1 0 |a Yutaka YAMAZAKI  |e author 
700 1 0 |a Manabu MORITA  |e author 
245 0 0 |a Relationship between acetaldehyde concentration in mouth air and tongue coating volume 
260 |b University of São Paulo,   |c 2015-02-01T00:00:00Z. 
500 |a 1678-7765 
500 |a 10.1590/1678-775720140223 
520 |a Objective Acetaldehyde is the first metabolite of ethanol and is produced in the epithelium by mucosal ALDH, while higher levels are derived from microbial oxidation of ethanol by oral microflora such as Candida species. However, it is uncertain whether acetaldehyde concentration in human breath is related to oral condition or local production of acetaldehyde by oral microflora. The aim of this pilot study was to investigate the relationship between physiological acetaldehyde concentration and oral condition in healthy volunteers. Material and Methods Sixty-five volunteers (51 males and 14 females, aged from 20 to 87 years old) participated in the present study. Acetaldehyde concentration in mouth air was measured using a portable monitor. Oral examination, detection of oral Candida species and assessment of alcohol sensitivity were performed. Results Acetaldehyde concentration [median (25%, 75%)] in mouth air was 170.7 (73.5, 306.3) ppb. Acetaldehyde concentration in participants with a tongue coating status score of 3 was significantly higher than in those with a score of 1 (p<0.017). After removing tongue coating, acetaldehyde concentration decreased significantly (p<0.05). Acetaldehyde concentration was not correlated with other clinical parameters, presence of Candida species, smoking status or alcohol sensitivity. Conclusion Physiological acetaldehyde concentration in mouth air was associated with tongue coating volume. 
546 |a EN 
690 |a Acetaldehyde 
690 |a Tongue 
690 |a Bacteria 
690 |a Cross-sectional studies 
690 |a Dentistry 
690 |a RK1-715 
655 7 |a article  |2 local 
786 0 |n Journal of Applied Oral Science, Vol 23, Iss 1, Pp 64-70 (2015) 
787 0 |n http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572015000100064&lng=en&tlng=en 
787 0 |n https://doaj.org/toc/1678-7765 
856 4 1 |u https://doaj.org/article/f53f9965b92747a295da62e98b99a58d  |z Connect to this object online.