Choice of adjuvant and antigen composition alters the immunogenic profile of a SARS-CoV-2 subunit vaccine

• Главные авторы: William R. Lykins (Автор), Jeroen Pollet (Автор), Jessica A. White (Автор), Brian Keegan (Автор), Leroy Versteeg (Автор), Ulrich Strych (Автор), Wen-Hsiang Chen (Автор), Raodoh Mohamath (Автор), Gabi Ramer-Denisoff (Автор), Sierra Reed (Автор), Samuel Beaver (Автор), Alana Gerhardt (Автор), Emily A. Voigt (Автор), Mark A. Tomai (Автор), Robert Sitrin (Автор), Robert K. M. Choy (Автор), Frederick J. Cassels (Автор), Peter J. Hotez (Автор), Maria Elena Bottazzi (Автор), Christopher B. Fox (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2024-02-01T00:00:00Z.
• Предметы: article
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Introduction: Since their introduction, adjuvanted recombinant subunit vaccines against COVID-19 have played a pivotal role in protecting global populations. Optimizing the immune response's quality, amplitude, and durability to these vaccines depends on the appropriate adjuvant choice and dose...