Probing the multitargeting potential of n-hexane fraction of Gongronema latifolium leaves in neurodegeneration via in vitro, GC-MS and in silico studies

• Main Authors: Gideon A. Gyebi (Author), Joseph C. Ejoh (Author), Oludare M. Ogunyemi (Author), Auza Moses Ibrahim (Author), Ibrahim M. Ibrahim (Author), Saheed O. Afolabi (Author), Gabriel O. Anyanwu (Author), Rotimi J. Ojo (Author), Olalekan B. Ogunro (Author), Badriyah S. Alotaibi (Author), Gaber El-Saber Batiha (Author)
• Format: Book
• Published: SpringerOpen, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Neurodegenerative disorders (NDDs) are associated with increased activities of brain acetylcholinesterase (AChE), butyrylcholinesterase (BChE) and monoamine oxidase (MAO) as well as Aβ-amyloid (Aβ) neurotoxicity; therefore, they offer a therapeutic option for the treatment of NDD...