New Insights into Behçet's Syndrome Metabolic Reprogramming: Citrate Pathway Dysregulation

• Main Authors: Anna Santarsiero (Author), Pietro Leccese (Author), Paolo Convertini (Author), Angela Padula (Author), Paolo Abriola (Author), Salvatore D'Angelo (Author), Faustino Bisaccia (Author), Vittoria Infantino (Author)
• Format: Bog
• Udgivet: Hindawi Limited, 2018-01-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

To date, a major research effort on Behçet's syndrome (BS) has been concentrated on immunological aspects. Little is known about the metabolic reprogramming in BS. Citrate is an intermediary metabolite synthesized in mitochondria, and when transported into the cytosol by the mitochondrial citr...