Comprehensive Analysis of Chemical Structures That Have Been Tested as CFTR Activating Substances in a Publicly Available Database CandActCFTR
Background: Cystic fibrosis (CF) is a genetic disease caused by mutations in CFTR, which encodes a chloride and bicarbonate transporter expressed in exocrine epithelia throughout the body. Recently, some therapeutics became available that directly target dysfunctional CFTR, yet research for more eff...
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Main Authors: | Manuel Manfred Nietert (Author), Liza Vinhoven (Author), Florian Auer (Author), Sylvia Hafkemeyer (Author), Frauke Stanke (Author) |
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Format: | Book |
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Frontiers Media S.A.,
2021-12-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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