Percutaneous absorption and brain distribution facilitation of borneol on tetramethylpyrazine in a microemulsion-based transdermal therapeutic system

In this study, we show that the percutaneous absorption and brain distribution of tetramethylpyrazine (TMP) is enhanced when combined with borneol (BN) in a microemulsion-based transdermal therapeutic system (ME-TTS). The formulation of the TMP and BN microemulsion (TEM-BN-ME) was optimized in skin...

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Main Authors: Xiaoge Hu (Author), Ning Cheng (Author), Jihui Zhao (Author), Xianghua Piao (Author), Yulu Yan (Author), Qibo Zhang (Author), Kuan Zhou (Author), Yongtai Zhang (Author), Nianping Feng (Author)
Format: Book
Published: Elsevier, 2019-05-01T00:00:00Z.
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