Acne inversa (Hidradenitis suppurativa): A review with a focus on pathogenesis and treatment

Acne inversa (AI) is a disabilitating chronic inflammatory disease with major negative impact on quality of life and significant co-morbidities. This is an important link to insights into immune dysfunction, which stimulated therapeutic approaches like tumor necrosis-α inhibitor therapy. This new of...

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Bibliographic Details
Main Authors: Uwe Wollina (Author), André Koch (Author), Birgit Heinig (Author), Thomas Kittner (Author), Andreas Nowak (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2013-01-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Uwe Wollina  |e author 
700 1 0 |a André Koch  |e author 
700 1 0 |a Birgit Heinig  |e author 
700 1 0 |a Thomas Kittner  |e author 
700 1 0 |a Andreas Nowak  |e author 
245 0 0 |a Acne inversa (Hidradenitis suppurativa): A review with a focus on pathogenesis and treatment 
260 |b Wolters Kluwer Medknow Publications,   |c 2013-01-01T00:00:00Z. 
500 |a 2229-5178 
500 |a 10.4103/2229-5178.105454 
520 |a Acne inversa (AI) is a disabilitating chronic inflammatory disease with major negative impact on quality of life and significant co-morbidities. This is an important link to insights into immune dysfunction, which stimulated therapeutic approaches like tumor necrosis-α inhibitor therapy. This new off-label drug treatment is particularly beneficial when used in combination with wide excision of inflamed skin and subcutaneous tissue. Retinoids have been reported to be helpful in secondary prevention. The standard of therapy in advanced cases is surgery with wide excisions and healing by secondary intention. This treatment results in significant reduction of complaints and achieves satisfactory body contouring. 
546 |a EN 
690 |a Acne inversa 
690 |a co-morbidities 
690 |a drug therapy 
690 |a hidradenitis suppurativa 
690 |a immune dysfunctions 
690 |a radical surgery 
690 |a retinoids 
690 |a tumor necrosis factor-α 
690 |a Dermatology 
690 |a RL1-803 
655 7 |a article  |2 local 
786 0 |n Indian Dermatology Online Journal, Vol 4, Iss 1, Pp 2-11 (2013) 
787 0 |n http://www.idoj.in/article.asp?issn=2229-5178;year=2013;volume=4;issue=1;spage=2;epage=11;aulast=Wollina 
787 0 |n https://doaj.org/toc/2229-5178 
856 4 1 |u https://doaj.org/article/f6af9a6b64314ba5a37be7b45d55824f  |z Connect to this object online.