In vitro Assessment of the DNA Damage Response in Dental Mesenchymal Stromal Cells Following Low Dose X-ray Exposure

• Main Authors: Niels Belmans (Author), Liese Gilles (Author), Jonas Welkenhuysen (Author), Randy Vermeesen (Author), Bjorn Baselet (Author), Benjamin Salmon (Author), Sarah Baatout (Author), Reinhilde Jacobs (Author), Stéphane Lucas (Author), Ivo Lambrichts (Author), Marjan Moreels (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Stem cells contained within the dental mesenchymal stromal cell (MSC) population are crucial for tissue homeostasis. Assuring their genomic stability is therefore essential. Exposure of stem cells to ionizing radiation (IR) is potentially detrimental for normal tissue homeostasis. Although it has be...