Diagnostic Value of Urinary Microalbumin Level in Postpartum Acute Kidney Injury

• Main Authors: Jian ZHANG (Author), Ning LI (Author), Wenling GUO (Author), Chuanyan MA (Author), Guangcheng ZHAO (Author)
• Format: Book
• Published: Tehran University of Medical Sciences, 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 2251-6085; 2251-6093
• Keywords: Postpartum acute kidney injury; Urinary microalbumin; Diagnosis; Public aspects of medicine; RA1-1270
• Source: Iranian Journal of Public Health, Vol 47, Iss 3 (2018)

Background: We aimed to explore the diagnostic value of urinary microalbumin (mALB) level in postpartum acute kidney injury. Methods: A total of 127 maternity patients were selected from December 2013 to January in 2016 in Binzhou Central Hospital, Binzhou, Shandong, China and divided into two groups: the kidney injury and normal kidney group. The dynamic changes and diagnostic value of urine microprotein in postpartum acute kidney injury were analyzed. Results: The postpartum mean arterial pressure of maternity patients in the kidney injury group was 104.3 ± 11.6 mmHg, which was significantly higher than that of the normal kidney group (P<0.05). The mean age of the kidney injury group was 32.3 ± 11.6 years, which was significantly higher than that of the normal kidney group (P=0.006). In the kidney injury group, the postpartum glomerular filtration rate (GFR) was 78.4 ± 11.5 mL/min, which was significantly lower than the normal group (P=0.001), and urinary microalbumin was 2.87 ± 1.24 mg/mmol·Cr. The difference was statistically significant (P=0.002). mALB/GFR, Cr, urinary mALB, and GFR were the independent risk factors of postpartum acute kidney injury. The area under the ROC curve for mALB/GFR was 0.759, whereas the area under the ROC curve for Cr was 0.681, which was smaller (P = 0.042). The area under the ROC curve of mALB was 0.785 (P=0.027), which was close to the area under the ROC curve of mALB/GFR. Conclusion: Urinary mALB test is noninvasive and has high diagnostic value for postpartum kidney injury.