Emergência de Klebsiella pneumoniae produtora de carbapenemase (KPC) em um hospital terciário Emergence of Klebsiella pneumoniae carbapenemase-producing (KPC) in a tertiary hospital

• Main Author: Valéria Martins Soares (Author)
• Format: Book
• Published: Sociedade Brasileira de Patologia Clínica, 2012-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 10.1590/S1676-24442012000400003; 1676-2444; 1678-4774
• Keywords: Klebsiella pneumoniae carbapenemase; Resistência bacteriana a antimicrobianos; Carbapenêmicos; Klebsiella pneumoniae carbapenemase; Antimicrobial resistance; Carbapenemase; Pathology; RB1-214
• Source: Jornal Brasileiro de Patologia e Medicina Laboratorial, Vol 48, Iss 4, Pp 251-253 (2012)

A resistência bacteriana é um problema frequente e importante no ambiente hospitalar. Oito cepas de Klebsiella pneumoniae produtoras de carbapenemase (KPC) foram isoladas de oito pacientes distintos, entre abril de 2009 e janeiro de 2011, no Hospital Júlia Kubitschek (HJK), localizado na cidade de Belo Horizonte, Brasil, seguindo os critérios definidos pelo Clinical and Laboratory Standards Institute (CLSI, 2009). Considerando o caráter emergente da KPC, torna-se importante seu rastreamento em isolados de enterobactérias com sensibilidade diminuída ao ertapenem.<br>Bacterial resistance is a frequent and major issue in nosocomial environment. In accordance with the standards proposed by the Clinical and Laboratory Standards Institute (CLSI, 2009), eight strains of Klebsiella pneumoniae (KPC) were isolated from eight distinct patients at Júlia Kubitschek Hospital (JKH), located in the city of Belo Horizonte, Brazil, between April 2009 and January 2011. As far as KPC emergence is concerned, its monitoring in Enterobacteriaceae isolates with decreased susceptibility to ertapenem has become highly important.