Escin's Action on Bradykinin Pathway: Advantageous Clinical Properties for an Unknown Mechanism?
Escin, extracted from horse chestnut (<i>Aesculus hippocastanum</i>) has anti-edema and anti-inflammatory effects. It is used to treat several clinical conditions, including venous insufficiency, pain, inflammation, and edema. Considering escin's pharmacodynamic, the inhibition of t...
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MDPI AG,
2024-09-01T00:00:00Z.
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LEADER | 00000 am a22000003u 4500 | ||
---|---|---|---|
001 | doaj_f79809d42f3b4a7bac1d945341f62c8e | ||
042 | |a dc | ||
100 | 1 | 0 | |a Gianmarco Marcianò |e author |
700 | 1 | 0 | |a Cristina Vocca |e author |
700 | 1 | 0 | |a Demirhan Dıraçoğlu |e author |
700 | 1 | 0 | |a Rotinda Özdaş Sevgin |e author |
700 | 1 | 0 | |a Luca Gallelli |e author |
245 | 0 | 0 | |a Escin's Action on Bradykinin Pathway: Advantageous Clinical Properties for an Unknown Mechanism? |
260 | |b MDPI AG, |c 2024-09-01T00:00:00Z. | ||
500 | |a 10.3390/antiox13091130 | ||
500 | |a 2076-3921 | ||
520 | |a Escin, extracted from horse chestnut (<i>Aesculus hippocastanum</i>) has anti-edema and anti-inflammatory effects. It is used to treat several clinical conditions, including venous insufficiency, pain, inflammation, and edema. Considering escin's pharmacodynamic, the inhibition of the bradykinin pathway represents a particular effect, decreasing the local edema and conferring an advantage in comparison to other compounds. In this narrative review, we described the effects of escin considering its effects on bradykinin pathway. | ||
546 | |a EN | ||
690 | |a escin | ||
690 | |a bradykinin | ||
690 | |a hippocastanum | ||
690 | |a inflammation | ||
690 | |a edema | ||
690 | |a venous insufficiency | ||
690 | |a Therapeutics. Pharmacology | ||
690 | |a RM1-950 | ||
655 | 7 | |a article |2 local | |
786 | 0 | |n Antioxidants, Vol 13, Iss 9, p 1130 (2024) | |
787 | 0 | |n https://www.mdpi.com/2076-3921/13/9/1130 | |
787 | 0 | |n https://doaj.org/toc/2076-3921 | |
856 | 4 | 1 | |u https://doaj.org/article/f79809d42f3b4a7bac1d945341f62c8e |z Connect to this object online. |