Anaplastic lymphoma kinase positive variant of anaplastic large cell lymphoma: A rare entity
Anaplastic large cell lymphoma (ALCL) is a distinct clinicopathological entity of non-Hodgkin's lymphoma, which has been included as a T-cell neoplasm in the World Health Organization classification, with peculiar features such as painless lymphadenopathy, swelling of extranodal and endoreticul...
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Main Authors: | , , , |
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Format: | Book |
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Wolters Kluwer Medknow Publications,
2014-01-01T00:00:00Z.
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Summary: | Anaplastic large cell lymphoma (ALCL) is a distinct clinicopathological entity of non-Hodgkin's lymphoma, which has been included as a T-cell neoplasm in the World Health Organization classification, with peculiar features such as painless lymphadenopathy, swelling of extranodal and endoreticular organs, intraoral swellings, and characteristic hallmark cells (eccentric, kidney-shaped, or horseshoe-shaped nuclei) and cluster of differentiation 30 (CD30) positivity. Thorough clinical, biochemical, immunohistochemical, histopathological, and radiological evaluation aids in accurate diagnosis and management of the disease. Here, we report a case of anaplastic lymphoma kinase positive variant of ALCL in a 13-year-old boy. |
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Item Description: | 0972-1363 0975-1572 10.4103/0972-1363.155640 |