Anaplastic lymphoma kinase positive variant of anaplastic large cell lymphoma: A rare entity

Anaplastic large cell lymphoma (ALCL) is a distinct clinicopathological entity of non-Hodgkin's lymphoma, which has been included as a T-cell neoplasm in the World Health Organization classification, with peculiar features such as painless lymphadenopathy, swelling of extranodal and endoreticul...

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Main Authors: Venkata Satya Ramesh Thummala (Author), Sreenidhi Banda (Author), Vinay Kumar Reddy Kundoor (Author), Kotya Naik Maloth (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2014-01-01T00:00:00Z.
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Summary:Anaplastic large cell lymphoma (ALCL) is a distinct clinicopathological entity of non-Hodgkin's lymphoma, which has been included as a T-cell neoplasm in the World Health Organization classification, with peculiar features such as painless lymphadenopathy, swelling of extranodal and endoreticular organs, intraoral swellings, and characteristic hallmark cells (eccentric, kidney-shaped, or horseshoe-shaped nuclei) and cluster of differentiation 30 (CD30) positivity. Thorough clinical, biochemical, immunohistochemical, histopathological, and radiological evaluation aids in accurate diagnosis and management of the disease. Here, we report a case of anaplastic lymphoma kinase positive variant of ALCL in a 13-year-old boy.
Item Description:0972-1363
0975-1572
10.4103/0972-1363.155640