Epithelioid trophoblastic tumor: Clinical presentation, diagnosis, and treatment

Epithelioid trophoblastic tumor (ETT) is a rare form of trophoblastic disease, which is characterized by high malignancy and a number of diagnostic features: a long interval between the last pregnancy and labor and the onset of the disease; a visual pattern at gynecological examination, relatively l...

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Bibliographic Details
Main Authors: D. A. Lisayev (Author), B. O. Toloknov (Author), E. E. Makhova (Author), I. V. Markina (Author)
Format: Book
Published: ABV-press, 2014-08-01T00:00:00Z.
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Summary:Epithelioid trophoblastic tumor (ETT) is a rare form of trophoblastic disease, which is characterized by high malignancy and a number of diagnostic features: a long interval between the last pregnancy and labor and the onset of the disease; a visual pattern at gynecological examination, relatively low β-chorionic gonadotropin (CG) levels, as well as the diffuse expression of cytokeratins-7 (+++) and -18 (+++), р63 (nuclear ++), E-cadherin (+++), EGFR (+), and CD-117(++) by tumor cells, as determined by immunohistochemical assay, and focal expression of CG (++) and PLAP (+) by these cells.
Item Description:1994-4098
1999-8627
10.17650/1994-4098-2010-0-2-84-88