Cover Image

Synthesis of tetrazole hybridized with thiazole, thiophene or thiadiazole derivatives, molecular modelling and antimicrobial activity

Background: Tetrazole-based derivatives and their electronic structures have displayed interesting antimicrobial activity. Methods: The tetrazole-based hybrids linked with thiazole, thiophene and thiadiazole ring systems have been synthesized through various chemical reactions. The computational met...

Full description

Saved in:

Bibliographic Details
Main Authors:	Matokah M. Abualnaja (Author), Adel I. Alalawy (Author), Omar M. Alatawi (Author), Ali H. Alessa (Author), Ahmad Fawzi Qarah (Author), Alaa M. Alqahtani (Author), Majid A. Bamaga (Author), Nashwa M. El-Metwaly (Author)
Format:	Book
Published:	Elsevier, 2024-03-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Thiadiazole-thiazole derivatives as potent anti-tubercular agents: Synthesis, biological evaluation, and In silico docking studies
by: Samin A. Shaikh, et al.
Published: (2024)

5-(Thiophen-2-yl)-1,3,4-thiadiazole derivatives: synthesis, molecular docking and in vitro cytotoxicity evaluation as potential anticancer agents
by: Gomha SM, et al.
Published: (2018)

Design, synthesis, and biological evaluation of thiazole/thiadiazole carboxamide scaffold-based derivatives as potential c-Met kinase inhibitors for cancer treatment
by: Xiang Nan, et al.
Published: (2023)

In vitro evaluation of tetrazoles as a novel class of Antimycobacterium tuberculosis agents
by: Bhaskar V.H, et al.
Published: (2012)

Novel Thiazolidine-2,4-dione-trimethoxybenzene-thiazole Hybrids as Human Topoisomerases Inhibitors
by: Maria Stefania Sinicropi, et al.
Published: (2023)

Discovery of new thymol-3,4-disubstituted thiazole hybrids as dual COX-2/5-LOX inhibitors with in vivo proof
by: Mostafa M. M. El-Miligy, et al.
Published: (2024)

Quinazolino-thiadiazoles as antimicrobial agents
by: Harun Patel, et al.
Published: (2018)

Analgesic Activity of Some 1,2,4-Triazole Heterocycles Clubbed with Pyrazole, Tetrazole, Isoxazole and Pyrimidine
by: Ramdas Bhanudas Pandhare, et al.
Published: (2013)

Design, synthesis, and evaluation of novel racecadotril-tetrazole-amino acid derivatives as new potent analgesic agents
by: Mehdi Asadi, et al.
Published: (2021)

Antimicrobial metal-based thiophene derived compounds
by: Shakeela Yasmeen, et al.
Published: (2017)

Novel tetrazole and cyanamide derivatives as inhibitors of cyclooxygenase-2 enzyme: design, synthesis, anti-inflammatory evaluation, ulcerogenic liability and docking study
by: Phoebe F. Lamie, et al.
Published: (2017)

Assessment of the potential risk of oteseconazole and two other tetrazole antifungals to inhibit adrenal steroidogenesis and peripheral metabolism of corticosteroids
by: Marie-Christin Jäger, et al.
Published: (2024)

Non-small cell lung cancer sensitisation to platinum chemotherapy via new thiazole-triazole hybrids acting as dual T-type CCB/MMP-9 inhibitors
by: Hassan Gamal, et al.
Published: (2024)

Antiparasitic Behavior of Trifluoromethylated Pyrazole 2-Amino-1,3,4-thiadiazole Hybrids and Their Analogues: Synthesis and Structure-Activity Relationship
by: Jeniffer do Nascimento Ascencio Camargo, et al.
Published: (2020)

Identification of Indazole-Based Thiadiazole-Bearing Thiazolidinone Hybrid Derivatives: Theoretical and Computational Approaches to Develop Promising Anti-Alzheimer's Candidates
by: Yousaf Khan, et al.
Published: (2023)

Thiophene-Based Compounds with Potential Anti-Inflammatory Activity
by: Ryldene Marques Duarte da Cruz, et al.
Published: (2021)

Synthesis, Cytotoxic Analysis, and Molecular Docking Studies of Tetrazole Derivatives via N-Mannich Base Condensation as Potential Antimicrobials
by: Atef Hatamleh A, et al.
Published: (2020)

Synthesis and Antimicrobial Evaluation of Certain Novel Thiazoles
by: Lakshmana Rao Krishna Rao Ravindranath, et al.
Published: (2013)

Synthesis and cytotoxicity evaluation of thiosemicarbazones and their thiazole derivatives
by: Saulo Feheiberg Pinto Braga, et al.

Thiazole-Based Thiosemicarbazones: Synthesis, Cytotoxicity Evaluation and Molecular Docking Study
by: Gomha SM, et al.
Published: (2021)

Synthetic thiophenes induce chromosomal damage and trigger apoptosis in human cancer cell lines
by: Filipe N. Franco, et al.
Published: (2022)

Thiazole-Bearing 4-Thiazolidinones as New Anticonvulsant Agents
by: Mariia Mishchenko, et al.
Published: (2020)

3-(1,2,3-Triazol-4-yl)-β-Carbolines and 3-(1<i>H</i>-Tetrazol-5-yl)-β-Carbolines: Synthesis and Evaluation as Anticancer Agents
by: João L. P. Ribeiro, et al.
Published: (2022)

Anticonvulsant activity of novel Schiff bases of thiadiazole derivatives
by: Ajit Kumar Pandey
Published: (2019)

Design, synthesis and biological evaluation of 1-Aryl-5-(4-arylpiperazine-1-carbonyl)-1H-tetrazols as novel microtubule destabilizers
by: Chao Wang, et al.
Published: (2021)

The Synthesis, In Vitro Bio-Evaluation, and In Silico Molecular Docking Studies of Pyrazoline-Thiazole Hybrid Analogues as Promising Anti-α-Glucosidase and Anti-Urease Agents
by: Yousaf Khan, et al.
Published: (2023)

Synthesis of New Thiazole-Privileged Chalcones as Tubulin Polymerization Inhibitors with Potential Anticancer Activities
by: Hamada Hashem, et al.
Published: (2024)

Evaluation of the interference of platelets in reticulocyte counting by flow cytometry using thiazole orange
by: Karina Augusta Viana, et al.

Synthesis and biological evaluation of thiazole derivatives as LbSOD inhibitors
by: Camila C. Bitencourt Brito, et al.
Published: (2019)

Synthesis and antimicrobial evaluation with DFT study for new thiazole derivatives
by: Sumayah Saadi Abbas, et al.
Published: (2018)

Synthesis and Structure Determination of Substituted Thiazole Derivatives as EGFR/BRAF<sup>V600E</sup> Dual Inhibitors Endowed with Antiproliferative Activity
by: Lamya H. Al-Wahaibi, et al.
Published: (2023)

In Vitro Anticancer Activity Screening of Novel Fused Thiophene Derivatives as VEGFR-2/AKT Dual Inhibitors and Apoptosis Inducers
by: Rana M. Abdelnaby, et al.
Published: (2022)

Synthesis and Evaluation of 3-Halobenzo[<i>b</i>]thiophenes as Potential Antibacterial and Antifungal Agents
by: Prerna J. Masih, et al.
Published: (2021)

Thiophene-Linked 1,2,4-Triazoles: Synthesis, Structural Insights and Antimicrobial and Chemotherapeutic Profiles
by: Nada A. El-Emam, et al.
Published: (2024)

Discovery of Novel Thiophene/Hydrazones: In Vitro and In Silico Studies against Pancreatic Cancer
by: Goknil Pelin Coskun, et al.
Published: (2023)

Synthesis of Novel 1,4- Dihydropyridine Derivatives Bearing Biphenyl-2'-Tetrazole Substitution as Potential Dual Angiotensin II Receptors and Calcium Channel Blockers
by: Javid Shahbazi Mojarrad, et al.
Published: (2011)

4-(Indol-3-yl)thiazole-2-amines and 4-ιndol-3-yl)thiazole Acylamines as Νovel Antimicrobial Agents: Synthesis, In Silico and In Vitro Evaluation
by: Sergei Simakov, et al.
Published: (2021)

One-Pot Synthesis of Novel Thiazoles as Potential Anti-Cancer Agents
by: Sayed AR, et al.
Published: (2020)

A review on progress of thiazole derivatives as potential anti-inflammatory agents
by: Kereyagalahally H. Narasimhamurthy, et al.
Published: (2024)

Continuous removal of thiophenic sulfur compounds from transportation fuels by using X zeolite
by: Jittima Kaewboran
Published: (2014)