MyD88 signalling is critical in the development of pancreatic cancer cachexia

• Main Authors: Xinxia Zhu (Author), Kevin G. Burfeind (Author), Katherine A. Michaelis (Author), Theodore P. Braun (Author), Brennan Olson (Author), Katherine R. Pelz (Author), Terry K. Morgan (Author), Daniel L. Marks (Author)
• Format: Book
• Published: Wiley, 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Up to 80% of pancreatic cancer patients suffer from cachexia, a devastating condition that exacerbates underlying disease, reduces quality of life, and increases treatment complications and mortality. Tumour‐induced inflammation is linked to this multifactorial wasting syndrome,...