Lucio's phenomenon: exuberant case report and review of Brazilian cases

Abstract Lucio's phenomenon is an uncommon reaction characterized by severe necrotizing cutaneous lesions that occurs in patients with Lucio's leprosy and lepromatous leprosy. It is considered by some authors as a variant of type 2 or 3 reaction. Death can occur because of blood dyscrasia...

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Main Authors: Rafael Henrique Rocha (Author), Paulo Sergio Emerich (Author), Lucia Martins Diniz (Author), Marcela Bahia Barretto de Oliveira (Author), Aline Neves Freitas Cabral (Author), Ana Cristina Vervloet do Amaral (Author)
Format: Book
Published: Sociedade Brasileira de Dermatologia, 2016-10-01T00:00:00Z.
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Summary:Abstract Lucio's phenomenon is an uncommon reaction characterized by severe necrotizing cutaneous lesions that occurs in patients with Lucio's leprosy and lepromatous leprosy. It is considered by some authors as a variant of type 2 or 3 reaction. Death can occur because of blood dyscrasia or sepsis. Precipitating factors include infections, drugs and pregnancy. We report a 31-year-old female patient exhibiting both clinical and histopathological features of lepromatous leprosy and Lucio's phenomenon presenting favorable response to treatment. We complement our report with a literature review of the Brazilian cases of Lucio's phenomenon published in Portuguese and English.
Item Description:0365-0596
10.1590/abd1806-4841.20164370