Population pharmacokinetic model with time‐varying clearance for lorlatinib using pooled data from patients with non‐small cell lung cancer and healthy participants
Abstract Lorlatinib, a selective inhibitor of anaplastic lymphoma kinase (ALK) and c‐ROS oncogene 1 (ROS1) tyrosine kinase, is indicated for the treatment of ALK‐positive metastatic non‐small cell lung cancer (NSCLC) following progression on crizotinib and at least one other ALK inhibitor, or alecti...
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Main Authors: | Joseph Chen (Author), Brett Houk (Author), Yazdi K. Pithavala (Author), Ana Ruiz‐Garcia (Author) |
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Format: | Book |
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Wiley,
2021-02-01T00:00:00Z.
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