Multiple adverse drug reactions during all-trans retinoic acid treatment for acute promyelocytic leukemia: differentiation syndrome, bradycardia, intestinal necrosis
All-trans retinoic acid (ATRA) induces complete remission in a high proportion of acute promyelocytic leukemia (APL). Nevertheless it is be associated with adverse drug reactions that might be life-threatening including differentiation syndrome, myocarditis, myositis, Sweet's syndrome and ulcer...
में बचाया:
| मुख्य लेखकों: | , , , , |
|---|---|
| स्वरूप: | पुस्तक |
| प्रकाशित: |
Open Exploration Publishing Inc.,
2020-04-01T00:00:00Z.
|
| विषय: | |
| ऑनलाइन पहुंच: | Connect to this object online. |
| टैग: |
टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!
|
MARC
| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | doaj_f81b7bb0fbde4ae383ba1ec13c60ae8b | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Valeria Ferla |e author |
| 700 | 1 | 0 | |a Mariarita Sciumé |e author |
| 700 | 1 | 0 | |a Umberto Gianelli2 |e author |
| 700 | 1 | 0 | |a Luca Baldini |e author |
| 700 | 1 | 0 | |a Nicola Stefano Fracchiolla |e author |
| 245 | 0 | 0 | |a Multiple adverse drug reactions during all-trans retinoic acid treatment for acute promyelocytic leukemia: differentiation syndrome, bradycardia, intestinal necrosis |
| 260 | |b Open Exploration Publishing Inc., |c 2020-04-01T00:00:00Z. | ||
| 500 | |a 10.37349/etat.2020.00007 | ||
| 500 | |a 2692-3114 | ||
| 520 | |a All-trans retinoic acid (ATRA) induces complete remission in a high proportion of acute promyelocytic leukemia (APL). Nevertheless it is be associated with adverse drug reactions that might be life-threatening including differentiation syndrome, myocarditis, myositis, Sweet's syndrome and ulcers. We describe a case of APL who during induction therapy developed ATRA syndrome, cardiac arrhythmia and multiple episodes of intestinal necrosis that required surgery. In particular, we report here for the first intestinal necrosis attributable to ATRA treatment in the absence of histological evidence of promyelocytes infiltration or leukocytoclastic vasculitis. | ||
| 546 | |a EN | ||
| 690 | |a acute promyelocytic leukemia | ||
| 690 | |a all-trans retinoic acid | ||
| 690 | |a adverse drug reaction | ||
| 690 | |a Internal medicine | ||
| 690 | |a RC31-1245 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Exploration of Targeted Anti-tumor Therapy, Vol 1, Iss 2, Pp 109-116 (2020) | |
| 787 | 0 | |n https://www.explorationpub.com/Journals/etat/Article/10027 | |
| 787 | 0 | |n https://doaj.org/toc/2692-3114 | |
| 856 | 4 | 1 | |u https://doaj.org/article/f81b7bb0fbde4ae383ba1ec13c60ae8b |z Connect to this object online. |