Acute Efavirenz Intoxication in a 16-year-old HIV Negative Girl: A Case Report and Literature Review
Background: There are only rare case reports that revealed the efavirenz (EFV) toxicity. Case Report: This study presents an acute intoxication with 12 g of efavirenz in a 16-year-old healthy girl whose main problem was dose-dependent neurotoxicity. No other serious EFV-related side effects were see...
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Main Authors: | , , |
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Format: | Book |
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Mazandaran University of Medical Sciences,
2024-12-01T00:00:00Z.
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Summary: | Background: There are only rare case reports that revealed the efavirenz (EFV) toxicity. Case Report: This study presents an acute intoxication with 12 g of efavirenz in a 16-year-old healthy girl whose main problem was dose-dependent neurotoxicity. No other serious EFV-related side effects were seen. Previous serious side effects of EFV were observed in HIV-infected patients who underwent long-term combination drug therapy. Conclusion: Accordingly, in terms of the key clinical messages, serious adverse effects of efavirenz are expected to be observed in long-term use in combination with other antiretroviral drugs. |
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Item Description: | 2423-4494 |