FISH-negative BCR::ABL1-positive e19a2 chronic myeloid leukaemia: the most cryptic of insertions

• Main Authors: Philippa C. May (Author), Alistair G. Reid (Author), Mark E. Robinson (Author), Jamshid S. Khorashad (Author), Dragana Milojkovic (Author), Simone Claudiani (Author), Genomics England Research Consortium (Author), Fenella Willis (Author), Jane F. Apperley (Author), Andrew J. Innes (Author)
• Format: Book
• Published: BMC, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Chronic myeloid leukaemia (CML) is one of the most well characterised human malignancies. Most patients have a cytogenetically visible translocation between chromosomes 9 and 22 which generates the pathognomonic BCR::ABL1 fusion gene. The derivative chromosome 22 ('Philadelp...