Effect of Antihelminthic Treatment on Vaccine Immunogenicity to a Seasonal Influenza Vaccine in Primary School Children in Gabon: A Randomized Placebo-Controlled Trial.

• Main Authors: Sina Brückner (Author), Selidji T Agnandji (Author), Stefan Berberich (Author), Emmanuel Bache (Author), José F Fernandes (Author), Brunhilde Schweiger (Author), Marguerite Massinga Loembe (Author), Thomas Engleitner (Author), Bertrand Lell (Author), Benjamin Mordmüller (Author), Ayola A Adegnika (Author), Maria Yazdanbakhsh (Author), Peter G Kremsner (Author), Meral Esen (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Helminth infections are a major public health problem, especially in the tropics. Infected individuals have an altered immune response with evidence that antibody response to vaccination is impaired. Hence, treatment of helminth infections before vaccination may be a simple intervention t...